The Whole Cannabis Plant works Synergisticly to Provide Medicine
In 1998 Shimon Ben-Shabatt
and Raphael Mechoulam coined the term the “Entourage Effect”.
This term explains how cannabis medicinally works with terpenes and
cannabinoids. They show the importance of all active ingredients of
cannabis for maximum effectivness.
The Entourage Effect is
directing a new thinking in cannabis medicine. In 1985 Marinol
singled out THC as the only active ingredient. Better results have
been shown by adding CBD with THC in the medicine Sativex. GW
Pharmeceuticals has incorporated the Entourage Effect in their
further research to make new cannabis medicine.
The cannabinoids and
terpenes in cannabis work together to maximize treatments. Raphael
Mechoulam said while introducing the Entourage Effect, “Very seldom
is the biological activity of the active constituent assayed together
with inactive 'entourage' compounds.” The variety of terpene and
cannabinoids profiles create the distinctive effects and strains of
the cannabis plant.
Source:
http://www.hightimes.com/read/understanding-effects-indica-vs-sativa
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