The Benefits of THCa

Tetrahydrocannabinolic Acid (THCa) is a cannabinoid found in raw marijuana. THCa begins to convert to THC while the cannabis flower is still on the plant. Therapeutic properties can be attributed to THCa including pain relief and reducing inflammation. The non-psychoactive effects allow patients to take at a higher dose for treatment.

Eating raw cannabis by juicing or tincture will provide ample amounts of THCa. Lab results of the flowers containing THC actually show how much THCa will be converted to THC when heated. Generally, the THCa consists of 5-25% of the marijuana plant itself.

Studies have shown that THCa has anti-inflammatory properties that can help arthritis, multiple sclerosis, pain, and gastrointestinal problems. (Source) Tetrahydrocannabinolic Acid can improve and reduce the effects of neurodegenerative disease. (Source) The antiemetic properties in THCa also helps patients with HIV\Aids and cancer. (Source) And finally, research has shown that THCa can slow or stop cancer growth in the prostate. (Source)

Source:

https://www.jstage.jst.go.jp/article/bpb/34/5/34_5_774/_article

https://ncbi.nlm.nih.gov/pubmed/22571976

http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.1981.tb13806.x/abstract

 https://ncbi.nlm.nih.gov/pmc/articles/PMC3570006/

Cannabis Use to Treat Eczema and Psoriasis

Many people that use cannabis to help with eczema and psoriasis. Marijuana helps with skin irritations by reducing inflammation. One third of the world population is thought to suffer from eczema.(Source)

Hemp seed, rich in linolenic acid (both α- and γ-), has shown benefits for reducing inflammation.(Source) Gastrointestinal problems have shown to increase skin problems. When the intestinal tract fails to absorb linolenic acid it is thought that skin abnormalities occur. Studies have shown that cannabis helps with gastrointestinal issues.

Auto immune deficiency can lead to skin abnormalities. Cannabis increases overall body immunity by being rich in globulin edestin. Immunity is increased by how it effects the endocannabinoid system, anandamide, and the 2-AG receptor.

Many dietary sources are rich in linolenic acid. Cannabis sets itself above the rest by the way it effects the endocannabinoid system. Abnormalities of cells attribute to skin problems. The endocannabinoid system regulates the cell proliferation, death and differentiation to maintain a homeostasis state.

http://sensiseeds.com/en/blog/cannabis-chrohttp://informahealthcare.com/doi/abs/10.1080/09546630510035832nic-skin-conditions/

http://www.ncbi.nlm.nih.gov/pubmed/17498413

http://informahealthcare.com/doi/abs/10.1080/09546630510035832

Testimonial - Thought I would Never Try Marijuana

Medical Marijuana Testimonial	After spending 24 years in the military I never thought I would ever use marijuana. I even voted against it. After being prescribed various medications for a number of my conditions I didn't see any improvements.I did research on all my medications and the side effects were disturbing. Read about medical marijuana, tried it and I am glad I did. It truly helps me.
Strains you Like	green crack, blue dream, fruit loops, mango kush, cotton candy, sour diesel, girl scout cookies
Conditions	Arthritis Gastrointestinal Migraine
Symptoms	Inflammation Muscle Spasms Pain: MuscleJoint Pain: Neuropathic Pain: Phantom Limb

The Terpene β-Caryophyllene in Cannabis

The Terpene β-Caryophyllene is the Only Approved Cannabinoid

The terpene caryophyllene gives a spicy peppery scent to some cannabis strains. It is also found in black pepper, cloves, cotton, hops, oregano and rosemary. β-Caryophyllene is a unique terpene categorized as a cannabinoid (BCP). This classification is from the way it effects the CB2 receptor. The relation with the receptor helps with anxiety, perception of pain and depression.(Source) Studies have also shown it to act as a neuroprotectant and reduce alcohol consumption.(Source)

Caryophyllene has been shown to help anxiety, arthritis, autoimmune disorders, inflammation, multiple sclerosis symptoms and gastrointestinal problems. Studies with β-Caryophyllene are promising for how it works as a cannabinoid without any psychotic effects. This is due to how it effects the CB2 receptors without effecting the CB1 receptors which give the marijuana high.(Source)

Strains that are high in caryophyllene include Super Silver Haze, Nevilles Haze and Hash Plant. Marijuana sniffing dogs are trained to look for the smell of Caryophyllene.(Source) Β-Caryophyllene is the first FDA approved cannabinoid.

Source:

http://www.leafscience.com/2014/07/08/b-caryophyllene-terpene-anxiety-depression/

http://www.sciencedirect.com/science/article/pii/S0031938414003400

http://en.wikipedia.org/wiki/Caryophyllene

http://www.sciencedirect.com/science/article/pii/S0091305714001956

The Benefits of Cannabis with Crohn's Disease

Crohn's Disease is a re-occurring inflammation of the gastrointestinal tract as well as an inflammatory Bowel Disease (IBD). Not to be confused with another IBD disease, ulcerative colitis, Crohn's affects any part of the gastrointestinal (GI) tract rather than only the colon or large intestine. Genetics, heredity and/or environmental factors have been shown to lead to Crohn's disease.  This disease affects around 700,000 Americans mostly of European descent. Symptoms of the disease are loss of appetite, weight loss, fatigue, night sweats, irregular menstrual cycle and fever. Inflammation of the GI Tract can also lead to diarrhea, bleeding, cramps, pain and constipation. (Source)

The enteric nervous system helps aid in gut function while the endocannabinoid system (ECS) helps to maintain gut motility, inflammation and sensation. Both systems contain Cannabinoid receptors CB1 and CB2 receptors making medical marijuana use a viable treat for Crohn's disease patients . (Source)

A pilot study of 32 patients of Crohn's disease was conducted at the International Association for Cannabis as Medicine conference at Leiden University in the Netherlands by Physicians in the Society of Cannabis Clinicians. Patients in this study showed  improvement in symptoms of vomiting, depression, nausea, gut pain, appetite, activity, fatigue, flareups and severity of flareups.(Source)

A study was completed at the University of Calgary in 2009 of 313 people with Inflammatory Bowel Disease (IBD).  The results of this study reported improvement of  abdominal pain, cramping, diarrhea, and joint paint in which 17.6% of the patients used cannabis using the inhalation method. (Source)

A study in 2011 with 30 Crohn's Disease patients showed that 21 reported improvements in all symptoms.(Source) in 2013, 21 patients involved in  a study smoking 2 marijuana cigarettes a day. showed improvement in sleep and appetite.  These patients with Crohn's disease were subjects that had not responded to other treatments(Source)

In a questionnaire given at a clinic with 191 Crohn's disease patients, 48% reported use of cannabis to reduce symptoms such as abdominal pain diarrhea and appetite were what the patients. Patients in the group that had abdominal surgery were more likely to use cannabis for treatment. (Source)

Source:

http://www.ccfa.org/what-are-crohns-and-colitis/what-is-crohns-disease/

http://www.medicaljane.com/2014/06/28/medical-marijuana-and-inflammatory-bowel-disease-ibd/#

http://www.beyondthc.com/wp-content/uploads/2012/07/Crohns05.pdf

http://www.ima.org.il/imaj/ViewArticle.aspx?aId=375

http://www.sciencedirect.com/science/article/pii/S1542356513006046

http://journals.lww.com/ibdjournal/Abstract/2014/03000/Cannabis_Use_Provides_Symptom_Relief_in_Patients.6.aspx

Cannabis Strains that are High in CBD

Most cannabis strains on the market are bred for their cannabinoid potency in THC, which is the active part that give a psycho effect. There are 85 active cannabinoids that are known in cannabis and cannabidiol or CBD is growing in popularity for it's high effectiveness for medicinal use without the psycho-active properties.

Treatment with Cannabidiol CBD

Cannabidiol in marijuana is the second most prevalent cannabinoid behind THC. At first it was thought the only benefit of CBD was to counteract the stoned effect that THC gives. However, CBD has been shown in research to give anti-inflammatory, analgesic and lower anxiety without the psycho-active effects that THC gives. These benefits have shown promising results for treatment in crohn's disease, PTSD, multiple sclerosis and a form of epilepsy called Dravet's Syndrome. Strains high in THC are usually at levels of 20% above, where CBD over 4% are known to be in high concentration. The FDA is approving a study this year to look at the effectiveness of CBD in children to hopefully make this a more accessible treatment.(Source)

Many patients are vocal about the importance of THC with CBD for complete effectiveness as a treatment. The government has acquired a patent for the benefits in THC, and research has showed it to help with appetite loss, nausea, multiple sclerosis and pain. Allowing to manage the percentage amount of THC and CBD gives the most effectiveness as well as also having control of how it is consumed. (Source)

Strains that are High in CBD

   The strains listed give different concentrations of CBD to THC ratios and also differentiate with their terpene properties to give different medicinal effects.

AC/DC - Sativa dominant 1:20 ratio of THC:CBD, a phenotype of Cannatonic

Cannatonic – Hybrid with 1:1 ratio. Origins are MK Ultra X and G-13 Haze.

Canna Sue – 13.8%CBD to 10.4%THC from Southern Humbolt Seed Company cross of Canna Tonic and Sour Tsunami

Charlotte's Web – Sativa dominant created by the Stanley brothers

Harlequin – Sativa Hybrid, registered 11.6%CBD to 8.4%THC (Source)

Harle Sue – Sativa Hybrid, registered 9.4%CBD to 6.7%THC, cross of Harlequin and Sour Tsunami

Jamaican Lion – Sativa with 1:1 ratio or better, cross between Mountain Lion and Yarders.(Source)

Omrita Rx – Indica dominant, 9.5% CBD to 11% THC, lots of leaves to juice, High in Beta Caryophylline.

Oracle* found to be identicle to AC/DC

Sour Tsunami – Sativa hybrid with 7.24%CBD to 4.32%THC ratio from Humboldt Seed Company

Women's Collective Stinky Purple

Swiss Gold – Sativa hybrid 7.2%CBD and 3.6%THC

Valentine X – Hybrid known to be highest CBD ratio 25:1, a phenotype of AC/DC

(Source)(Source)

Source:

http://www.projectcbd.org/medicine/strain-library/

http://www.leafly.com/news/lifestyle/whats-the-deal-with-these-high-cbd-strains

http://www.mpp.org/assets/documents/low-or-no-thc-high-cbd.html

http://synergycbd.com/cdb-rich-strains/

http://www.hydrocanna.com/showthread.php?t=9683

The Benefits of Cannabis for Celiac Disease

Celiac Disease is when the immune system attacks the body when gluten is ingested, which is found in wheat, barley or rye. In America, every 1 in 133 people contract Celiac Disease. The small intestine gets inflammation with celiac disease, and destroys the intestinal lining. This results in not fully digested food moving to the large intestines that produces bloating, cramping, gas and abdominal pain.(

Cannabis can treat some symptoms of celiac disease allowing for a more normal lifestyle. Marijuana can slow the muscle spasms and contractions to slow the movement down of food and also the liquid secretions to mitigate diarrhea. Many celiac patients describe pain due to the cramping that Marijuana can ease. Marijuana can also increase appetite and help absorb nutrients from the food.(Source)

Cannabinoids in cannabis interact with CB1 and CB2 receptors in the gastrointestinal system called the enteric nervous system and the CB1 & CB2 receptors in the brain. Both tetrahydrocannabinol (THC) and cannabidiol (CBD) cannabinoids are beneficial for treatment of celiac disease in cannabis. THC helps to slow down the digestion and movement of food going through the digestive tract too fast. CBD works with the CB2 receptors to reduce inflammation and help the immune cells in the digestive tract.(Source) CBD also helps to activate the THC into helping the intestinal motility.(Source) and (Source)

Source:

http://patients.gi.org/topics/celiac-disease/

http://pharmcannabis.com/documents/pertwee-2001.pdf

http://pharmcannabis.com/documents/usai-1997.pdf/

http://pharmcannabis.com/documents/luft-2007.pdf

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631143/

Cannabis as a Treatment for Diabetes

Diabetics can have many reasons to use cannabis as a way to reduce diabetes related problems. Here is a bullet point list of the problems that diabetics face and how marijuana can help from letfreedomgrow.com:

• Increases Blood Flow to Extremities - Cannabis inhibits the overproduction of prostoglandins, a hormone that dilates and constricts blood flow. Cannabis is a vasodialator that helps blood flow. Marijuana is a powerful antioxidant which helps decrease free radical damage and helps inflammation. For these reasons it allows cannabis to be a great treatment for arterial inflammation, common in diabetics. Topical creams on the extremities can help with instant relief.


• Over Time Reduces Blood Pressure – This is in conjunction with the previous from being a vasodialator. If cooking butter and oil is replaced with Cannabis oil and butter, the saturated fats from the old method of cooking will be eliminated and replaced with essential fatty acids.


• Muscle Cramps and Gastro Intestinal Upset – Many diabetics have these symptoms which are helped by cannabis for its ability to be neuroprotective. Cannabis helps the nerve covering from inflammation. Cannibidiol form of cannabis is best known for counteracting spasms.


• Blood Sugar Levels - One problem with research on cannabis is the criminalization of the drug that inhibits proper research to find if a treatment is conclusive or not. Sugar level may be regulated through cannabis from a reduction in Catecholamines. This is a hormone from the adrenal gland that produces epinephrine ( adrenalin ), norepinephrine and dopamine from emotional stress. Cannabis cookies can be used if in moderation to help control blood sugar levels.


• Restless Leg Syndrome RLS – Many diabetics suffer from restless leg syndrome and the cramping of the muscles that may be a result from the nervous system can be reduced by Cannabis in the way it controls the prostoglandins to relax muscles and it's neuroprotective properties. Using a nightime vapor or smoking before sleeping can reduce the symptoms, with the strains of Oregon 90, Lemon Haze, and White Berry being the best.

OUTCO is San Diego's only legally licensed medical marijuana dispensary offering FREE Delivery and Accepting Debit Cards.

Source:
http://www.letfreedomgrow.com/cmu/diabetes_5.htm

What is Tetrahydrocannabinol (THC)

When Cannabis is dried and then heated it does a chemical reaction that turns it into Tetrahyrocannabinol popularly known as THC. In this form, it becomes a narcotic psychoactive drug that is used primarily as a pain killer. The visual look is a clear water like solid (white) that when warmed up is sticky.

THC is well known to aid in increased appetite and reduce nausea. It stimulates the hypothalamus by CB1 activity to give interest to food as well as the ghrelin hormones that are in the gastronomical tract that induces the feeling of hunger. This affect helps cancer and AIDS survivors to gain an appetite.

THC has shown very good results in helping with multiple sclerosis symptoms. Studies have shown that especially oral cannabis, and good findings of THC help to reduce rigid or stiff muscles also known as spastic muscles, in reducing pain and spasms, and bladder dysfunction.

With marijuana is criminalized in many places, there is a lack of research and studies for possible more cures due to the legality of it. Studies for Parkinson's, Huntington, Alzheimer's diseases as well as Tourette's syndrome, Cervical Dystonia, and Epilepsy all have inconclusive results from studies from the lack of ability to do research.

OUTCO is San Diego's only legally licensed medical marijuana dispensary offering FREE Delivery and Accepting Debit Cards.

Source:
http://en.wikipedia.org/wiki/Tetrahydrocannabinol