The Benefits of THCa

Tetrahydrocannabinolic Acid (THCa) is a cannabinoid found in raw marijuana. THCa begins to convert to THC while the cannabis flower is still on the plant. Therapeutic properties can be attributed to THCa including pain relief and reducing inflammation. The non-psychoactive effects allow patients to take at a higher dose for treatment.

Eating raw cannabis by juicing or tincture will provide ample amounts of THCa. Lab results of the flowers containing THC actually show how much THCa will be converted to THC when heated. Generally, the THCa consists of 5-25% of the marijuana plant itself.

Studies have shown that THCa has anti-inflammatory properties that can help arthritis, multiple sclerosis, pain, and gastrointestinal problems. (Source) Tetrahydrocannabinolic Acid can improve and reduce the effects of neurodegenerative disease. (Source) The antiemetic properties in THCa also helps patients with HIV\Aids and cancer. (Source) And finally, research has shown that THCa can slow or stop cancer growth in the prostate. (Source)

Source:

https://www.jstage.jst.go.jp/article/bpb/34/5/34_5_774/_article

https://ncbi.nlm.nih.gov/pubmed/22571976

http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.1981.tb13806.x/abstract

 https://ncbi.nlm.nih.gov/pmc/articles/PMC3570006/

The Link between Cannabis and Breast Milk

Babies with their pacifiers and munchies after marijuana may go hand in hand. Cannabis and breast milk both effect the endocannabinoid system. Cannabinoids aid the body in creating a stable internal environment. The cannabinoids in breast milk provide health benefits that help babies grow and thrive.

A human embryo at 14 weeks of gestation starts forming cannabinoid receptors. By twenty weeks, the receptors grow at a rapid rate and start to function. Research suggests that the early formation helps to mature the nervous system.(Source)

The 2004 European Journal of Pharmacology article stated that "endocannabinoids have been detected in maternal milk and activation of CB1 (cannabinoid receptor type 1) receptors appears to be critical for milk sucking.”(Source) The desire to suck is integral to the life-affirming need for nourishment.

Some of the same active cannabinoids found in marijuana are in high concentration in breast milk. The endocannabinoid system boosts immunity, reduces inflammation, relieves pain, and increases appetite by regulating the internal systems of the body.

Source:

http://www.sciencedirect.com/science/article/pii/S0014299904007423

http://pharmrev.aspetjournals.org/content/58/3/389.full#title49

http://www.naturalnews.com/036526_cannabinoids_breast_milk_THC.html

http://www.cannabiscure.info/files/cannabis_breastmilk.htm

Harlequin Strain

Harlequin Marijuana Strain is High in CBD

Harlequin strain is for patients of medical marijuana looking for high pain relief. Harlequin is known for its high potency of the cannabinoid CBD. A ratio of 5:2 CBD to THC gives medication that is low in psycho-active sedation. Having some THC allows for the analgesic to be more effective than other strains that are void of THC. Harlequin is 75% sativa dominant which gives the effects of alertness while giving the ability to relax.

The Harlequin strain is a cross between the Columbian Gold, Swiss and Thai sativa with a Nepalese Indica Landrace strain. The smell has been described as sweet and tropical while the taste is fairly bland to sweet. The buds are thick with trichome orange hairs which overtake the green in the bud. Most strains while being cultivated increase in CBD while maturing. Harlequin is unique in that its highest concentration of CBD is earlier and diminishes with maturity.

OUTCO typically stocks Harlequin as a tincture for patients. Our staff in El Cajon just outside of San Diego is knowledgeable and compassionate to care for their members needs. Patients describe Harlequin for helping pain, seizures, anxiety, stress, nausea and muscle spasms. Please stop by or contact us for individual attention to your questions and needs.

Source:

http://www.leafly.com/sativa/harlequin

http://www.marijuana.com/news/2013/08/harlequin-marijuana-strain-review-and-photos-high-in-cbd-low-in-thc/

The Benefits of Cannabis and Osteoporosis

Benefits of Cannabis for Osteoporosis

54 million Americans suffer from Osteoporosis. It is a disease meaning “porous bone”. The holes in the bones can result in broken bones from minor accidents.(Source) Experts believe cannabis can slow the progression of tissue loss leading to Osteoporosis. This is from findings of how interactions with the CB1 and CB2 receptors maintain bone density.

Cannabis works along with the endocannabinoid system to effect the CB1 and CB2 receptors. CB1 receptors are in the skeletal nerve terminals. They regulate the bone formation. CB2 receptors initiate bone formation while also slowing bone resorption.(Source)

Bone metabolism is natural in mammals where the minerals in the bone are renewed. Osteoblasts are bone forming cells. Osteoclasts are bone resorbing cells. Osteoporosis occurs when the bone formation is reduced and fat can accumulate in the bone marrow.

Research shows two findings where associations with the CB2 receptors relate to osteoporosis. In one study, CB2 mutant mice resulted in low bone mass. The other shows a tie with the gene CNR2 that encodes the CB2 receptor. When the CNR2 gene is compromised it increases the tendency for postmenopausal osteoporosis. Bone loss slows when a cannabinoid drug is given to the mutant mice or women with postmenopausal symptoms.(Source)

A study by the Arthritis Research Campaign looked at the CB1 receptor in mice with bone loss. They also investigated the reasoning behind an increase in fat cells in marrow with aging bones. Osteoporosis was slowed when the mice were given treatment with cannabinoids to increase CB1 receptor function. First, the CB1 receptors regulated the osteoclast cells activity, slowing down the resorption. Secondly, the CB1 receptors were able to differentiate between the osteoblast and fat cells. This resulted in the osteoblast cells being increased and the fat cells decreasing.(Source)

The study done by Stuart Ralston, from the University of Edinburgh said:

"This is an exciting step forward, but we must recognize that these are early results and more tests are needed on the effects of cannabis in humans to determine how the effects differ with age in people. We plan to conduct further trials soon and hope the results will help to deliver new treatments that will be of value in the fight against osteoporosis." (Source)

Source:

http://nof.org/articles/7

http://www.ncbi.nlm.nih.gov/pubmed/19634029

http://www.ncbi.nlm.nih.gov/pubmed/18426503

http://www.ncbi.nlm.nih.gov/pubmed/19656492

http://news.bbc.co.uk/2/hi/uk_news/scotland/edinburgh_and_east/8199007.stm