A Connection between Fish Oil and Cannabis

Scientists have long since established that fish oil is very beneficial to your diet. Being rich in Omega-3, fish oil is similar to cannabis. (Source) Omega-3 comes in the form of DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid). (Source) New research shows that DHA effects the cannabinoid receptors CB1 and CB2. (Source)

When DHA is ingested, it is converted into docosahexaenoyl ethanolamide (DHEA) using the same pathways as anandamide. (Source) Researchers believe that this conversion creates the DHA’s beneficial qualities. This relationship allows Omega 3 to affect the sCB2 receptors, which can help decrease inflammation in the body. This new research is groundbreaking; it shows that fish can affect the endocannabinoid system. (Source)

Omega 3 is used to repair both the body and the cardiovascular system. The conversion of Omega 3 to (DHEA) has been proven to help with strokes, diabetes, and high blood pressure. Platelet-leukocyte aggregate formations at higher levels are precursors to heart attacks, as well as other cardiovascular problems. Introducing DHEA into the body reduces the platelet-leukocyte count in the blood. (Source)

Source:

http://en.wikipedia.org/wiki/Hemp_oil

http://www.researchgate.net/publication/51493529_Decoding_functional_metabolomics_with_docosahexaenoyl_ethanolamide_%28DHEA%29_identifies_novel_bioactive_signals

http://www.life-enhancement.com/magazine/article/2513-remarkable-new-findings-when-fish-oils-meet-cannabis-receptors-a-result-is-powerful-protection-of

Yang et al. Decoding functional metabolomics with docosahexaenoyl ethanolamide (DHEA) identifies novel bioactive signals. J Biol Chem 286(36):31532-41 (2011).

The Benefits of the Terpene 1,8 Cineole in Cannabis

Cineole also known as eucalyptol is an essential oil found in rosemary, eucalyptus and cannabis. It is a monoterpene naturally found that is safe in low concentrations. Cineole contributes to an “Entourage Effect” to support other medicinal values of marijuana.

Cineole helps the blood-brain barrier to allow other cannabinoids to penetrate more readily into the bloodstream.(Source) This allows it to aid in topical applications for pain and inflammation.(Source) It has also shown to help with circulation.(Source) Cineole affects the GABA receptors of the brain creating a balance in mood.(Source)

Cineole is known to have a spicy, camphor scent that is refreshing like rosemary. It is generally found more in sativa strains being known to give energy and an uplifting effect. Strains like Super Silver Haze, ChemDawg, and Bubba Kush are known to be high in eucalyptol.

Source:

https://www.icmag.com/ic/showthread.php?t=275717

http://www.feingold.org/Research/PDFstudies/Aoshima1999-open.pdf

http://link.springer.com/article/10.1007/s10886-005-8393-0

http://www.hindawi.com/journals/ecam/2013/502727/

http://theida.com/ew/wp-content/uploads/2010/10/Neuropathies-Essential-oils-show-promising-results-in-the-fight-against-symptoms.pdf

The Benefits of the Terpene p-Cymene in Cannabis

p-Cymene is a terpene found in cannabis at a low dosage. It is a volatile monoterpene that an essential oil found in coriander, cumin, oregano, eucalyptus, thyme and cannabis. High concentrations of p-Cymene can cause nausea, headaches, agitation and even loss of consciousness.

Used in its natural form in low concentrations it benefits as an antimicrobial and fragrance.(Source)

Cannabis has a low concentration of p-Cymene allowing it to be safe for consumption. The terpene can give a carrot or orange odor. It has antimicrobial, antifungal and AchE inhibiting properties.(Source) The inhibition of AchE prolongs the duration of the neurotransmitter Acetylcholine. This neurotransmitter can lower blood pressure by inhibiting cardiac muscle to contract.(Source) It also is used during eye surgery to make the eye muscles contract and constrict the pupil.(Source)

Source:

http://beneforce.com/Constituent/Constituent-pages/p-cymene.htm

http://www.biomedcentral.com/1471-2180/5/36

https://www.icmag.com/ic/showthread.php?t=295057

http://en.wikipedia.org/wiki/Acetylcholine

http://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0008808/

The Benefits of Cannabis and Hemophilia A

Hemophilia A is the lack of the blood to clot. This can lead to prolonged bleeding with wounds as well as internal bleeding problems. People with Hemophilia experience conditions that can be relieved with medical marijuana. These include:

• Bruising and swelling in soft tissue and muscle
• Headaches
• Fatigue
• Inflammation
• Swollen Joints
• Pain
• Nausea
• Stiff and Tight Joints

Traditionally opiate drugs are prescribed for treatment to treat swelling. Side-effects of NSAID are nausea, diarrhea, loss of appetite and constipation. Long-term effects of these narcotics can be addiction and damage to the liver and kidneys.

Cannabis can treat the symptoms of Hemophilia but it does not cure. Marijuana has clinical proof to treat inflammation, increase appetite, pain, nausea, headaches and joint pain. Marijuana is a safe alternative to opiate medication for its lower addiction rate and less side-effects.

Source:

http://medicalmarijuana.com/medical-marijuana-treatments/Hemophilia-A

https://www.marijuanadoctors.com/content/ailments/view/34?ailment=hemophilia-a

Cardiovascular Effects from Cannabis

Cardiovascular Effects from Cannabis

Studies have shown that marijuana in humans can increase heart rate and blood pressure moderately with first initial use. With regular use of cannabis these initial cardiovascular effects rapidly go away. Regular exposure to cannabis shows results of reduced blood pressure, reduced heart rate and increased vasodilation.(Source) Lowered heart rate and blood pressure is also seen in animals studies with cannabis.(Source)

Cannabinoids affect a group of lipids and receptors that control the endocannabinoid system. Anandamide is an endocannabinoid messenger molecule that helps control the heart rate and blood pressure. One way it effects the cardiovascular system is by vasodilation, or enlarging the blood vessels. Vasodilation occurs from a relaxation of artery walls to allow a larger volume of blood flow.(Source)

Dr. Phillip Leveque leads a medical marijuana doctor group with over 100,000 patients. They have found the increase in heart rate and blood pressure to be low and tolerable. In their group they have no reports of dangerous clinical hypertension. For his personal patients they average an age of 48 and have a lower percentile of hypertension than most people of that age not using marijuana.(Source) The first use of cannabis has shown to be safe for patients but still advised to be recommended by a doctor.(Source)

Source:

http://www.ncbi.nlm.nih.gov/pubmed/11106789

http://norml.org/library/item/hypertension

http://circ.ahajournals.org/content/110/14/1996.full

http://onlinelibrary.wiley.com/doi/10.1002/j.1552-4604.2002.tb06004.x/abstract

http://www.salem-news.com/articles/march142010/hypension-mmj.php

The Benefits of Cannabigerol (CBG)

  Cannabigerol CBG is a cannabinoid in marijuana that has medicinal properties. Found in low concentrations in many strains of cannabis it is often overlooked. CBG works in conjunction with THC to tone down the paranoia feeling.(Source) Alone it aids in treatment to depression, tumors, inflammatory bowel disease, glaucoma, bacteria infections, high blood pressure, reduce blood clotting, anxiety and muscle tension.

   Research has proven many treatments from Cannabigerol. Here is a list of the numerous benefits of CBG:

Depression: GW Pharma has a patent for the use of Cannabigerol CBG to treat clinical depression.(Source)

Cancer \Tumors: New research this year has shown that CBG reduces cancer cells and tumors in the colon.(Source)

Inflammatory Bowel Disease: CBG reduced inflammation and over-production of nitric oxide which can lead to sustained IBD.(Source)

Glaucoma: CBG shows promising treatment for glaucoma by relieving ocular pressure. More importantly CBG showed 2-3 times the benefit of eye drainage than other medicines.(Source)

Bacterial Infections: Bacterial infections have been treated including MRSA.(Source)

Reduce Heart Rate and Blood Clotting: Has shown as a proven treatment for the way it reduces platelet aggregation.(Source)

Anxiety and Muscle Tension: CBG is able to treate with it's ability to inhibit GABA production.(Source)

Cannabis initially starts with creating cannabinoid cannabigerolic acid (CBGa). This is typically broken down with exposure to air and UV light into THCa, CBDa or CBCa. If it remains as CBGa, then it will convert to CBG when heated. Some industrial strains retain the CBGa with as much as a 94% concentration. It is thought this strain has a recessive gene that doesn't allow the conversion to the THCa, CBDa or CBCa. Currently some growers are using this knowledge to create strains rich in CBG like the Mickey Kush Strain.

Source:

http://www.medicaljane.com/2013/08/03/cannabigerol-cbg-is-a-minor-cannabinoid-with-major-impact/

http://www.ncbi.nlm.nih.gov/pubmed/25269802

http://www.sciencedirect.com/science/article/pii/S0006295213000543

http://www.google.com/patents/CA2655094C?cl=en

http://www.amazon.com/Cannabis-Therapeutics-HIV-AIDS-Journal/dp/0789016990/ref=sr_1_1?s=books&ie=UTF8&qid=1418758497&sr=1-1&keywords=9780789016997

http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.1989.tb06345.x/abstract

Cannabis as a Treatment for Diabetes

Diabetics can have many reasons to use cannabis as a way to reduce diabetes related problems. Here is a bullet point list of the problems that diabetics face and how marijuana can help from letfreedomgrow.com:

• Increases Blood Flow to Extremities - Cannabis inhibits the overproduction of prostoglandins, a hormone that dilates and constricts blood flow. Cannabis is a vasodialator that helps blood flow. Marijuana is a powerful antioxidant which helps decrease free radical damage and helps inflammation. For these reasons it allows cannabis to be a great treatment for arterial inflammation, common in diabetics. Topical creams on the extremities can help with instant relief.


• Over Time Reduces Blood Pressure – This is in conjunction with the previous from being a vasodialator. If cooking butter and oil is replaced with Cannabis oil and butter, the saturated fats from the old method of cooking will be eliminated and replaced with essential fatty acids.


• Muscle Cramps and Gastro Intestinal Upset – Many diabetics have these symptoms which are helped by cannabis for its ability to be neuroprotective. Cannabis helps the nerve covering from inflammation. Cannibidiol form of cannabis is best known for counteracting spasms.


• Blood Sugar Levels - One problem with research on cannabis is the criminalization of the drug that inhibits proper research to find if a treatment is conclusive or not. Sugar level may be regulated through cannabis from a reduction in Catecholamines. This is a hormone from the adrenal gland that produces epinephrine ( adrenalin ), norepinephrine and dopamine from emotional stress. Cannabis cookies can be used if in moderation to help control blood sugar levels.


• Restless Leg Syndrome RLS – Many diabetics suffer from restless leg syndrome and the cramping of the muscles that may be a result from the nervous system can be reduced by Cannabis in the way it controls the prostoglandins to relax muscles and it's neuroprotective properties. Using a nightime vapor or smoking before sleeping can reduce the symptoms, with the strains of Oregon 90, Lemon Haze, and White Berry being the best.

OUTCO is San Diego's only legally licensed medical marijuana dispensary offering FREE Delivery and Accepting Debit Cards.

Source:
http://www.letfreedomgrow.com/cmu/diabetes_5.htm