The Benefits of Cannabis with Asthma

It seems hard to believe that smoking marijuana can help asthma. Unlike smoking nicotine that constricts the lung passageways, THC in cannabis expands the airways. Amazingly, cannabis consumed by smoking has been shown to reduce asthma symptoms.

Asthma attacks are muscle contractions. Restricted breathing is initiated from a signaling molecule called acetycholine. Dr. Tashkin, a lung expert from UCLA, studies the use of cannabis for asthma patients. He stated that traditional asthma medications “prevent the acetycholine from binding to its receptor. But THC works proximal to that. It doesn't have any competitive effect for binding to receptors. It just prevents the acetylcholine from being released.”

Different ways of consuming cannabis have shown a variety of results with asthma treatment. Taken orally, it is not strong enough and takes too long to be effective. Traditional asthma inhalers using THC make people cough. This is due to THC being a large enough molecule to cause a cough response. Smoking marijuana can offer immediate asthma relief. This method is not ideal due to noxious chemicals that can cause inflammation to the respiratory tissue. The best effective method is with THC being delivered through a vaporizer.

A twenty year study with people that suffer with asthma showed decrease in symptoms from cannabis use.(Source) Cannabis has been found to be a bronchodilator.(Source) Currently medicine including marijuana targets short-term asthma attacks. Researchers are looking into the possibility of cannabis providing a long-term treatment for asthma.(Source)

Source:

http://jama.jamanetwork.com/article.aspx?articleid=1104848

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1429361/

https://www.leafly.com/news/health/can-cannabis-help-asthma-patients-27df

http://www.leafscience.com/2014/02/04/study-explains-marijuana-isnt-bad-asthma/

Cannabis Use to Treat Eczema and Psoriasis

Many people that use cannabis to help with eczema and psoriasis. Marijuana helps with skin irritations by reducing inflammation. One third of the world population is thought to suffer from eczema.(Source)

Hemp seed, rich in linolenic acid (both α- and γ-), has shown benefits for reducing inflammation.(Source) Gastrointestinal problems have shown to increase skin problems. When the intestinal tract fails to absorb linolenic acid it is thought that skin abnormalities occur. Studies have shown that cannabis helps with gastrointestinal issues.

Auto immune deficiency can lead to skin abnormalities. Cannabis increases overall body immunity by being rich in globulin edestin. Immunity is increased by how it effects the endocannabinoid system, anandamide, and the 2-AG receptor.

Many dietary sources are rich in linolenic acid. Cannabis sets itself above the rest by the way it effects the endocannabinoid system. Abnormalities of cells attribute to skin problems. The endocannabinoid system regulates the cell proliferation, death and differentiation to maintain a homeostasis state.

http://sensiseeds.com/en/blog/cannabis-chrohttp://informahealthcare.com/doi/abs/10.1080/09546630510035832nic-skin-conditions/

http://www.ncbi.nlm.nih.gov/pubmed/17498413

http://informahealthcare.com/doi/abs/10.1080/09546630510035832

Testimonial - Thought I would Never Try Marijuana

Medical Marijuana Testimonial	After spending 24 years in the military I never thought I would ever use marijuana. I even voted against it. After being prescribed various medications for a number of my conditions I didn't see any improvements.I did research on all my medications and the side effects were disturbing. Read about medical marijuana, tried it and I am glad I did. It truly helps me.
Strains you Like	green crack, blue dream, fruit loops, mango kush, cotton candy, sour diesel, girl scout cookies
Conditions	Arthritis Gastrointestinal Migraine
Symptoms	Inflammation Muscle Spasms Pain: MuscleJoint Pain: Neuropathic Pain: Phantom Limb

The Benefits of Cannabis and Hemophilia A

Hemophilia A is the lack of the blood to clot. This can lead to prolonged bleeding with wounds as well as internal bleeding problems. People with Hemophilia experience conditions that can be relieved with medical marijuana. These include:

• Bruising and swelling in soft tissue and muscle
• Headaches
• Fatigue
• Inflammation
• Swollen Joints
• Pain
• Nausea
• Stiff and Tight Joints

Traditionally opiate drugs are prescribed for treatment to treat swelling. Side-effects of NSAID are nausea, diarrhea, loss of appetite and constipation. Long-term effects of these narcotics can be addiction and damage to the liver and kidneys.

Cannabis can treat the symptoms of Hemophilia but it does not cure. Marijuana has clinical proof to treat inflammation, increase appetite, pain, nausea, headaches and joint pain. Marijuana is a safe alternative to opiate medication for its lower addiction rate and less side-effects.

Source:

http://medicalmarijuana.com/medical-marijuana-treatments/Hemophilia-A

https://www.marijuanadoctors.com/content/ailments/view/34?ailment=hemophilia-a

The Terpene β-Caryophyllene in Cannabis

The Terpene β-Caryophyllene is the Only Approved Cannabinoid

The terpene caryophyllene gives a spicy peppery scent to some cannabis strains. It is also found in black pepper, cloves, cotton, hops, oregano and rosemary. β-Caryophyllene is a unique terpene categorized as a cannabinoid (BCP). This classification is from the way it effects the CB2 receptor. The relation with the receptor helps with anxiety, perception of pain and depression.(Source) Studies have also shown it to act as a neuroprotectant and reduce alcohol consumption.(Source)

Caryophyllene has been shown to help anxiety, arthritis, autoimmune disorders, inflammation, multiple sclerosis symptoms and gastrointestinal problems. Studies with β-Caryophyllene are promising for how it works as a cannabinoid without any psychotic effects. This is due to how it effects the CB2 receptors without effecting the CB1 receptors which give the marijuana high.(Source)

Strains that are high in caryophyllene include Super Silver Haze, Nevilles Haze and Hash Plant. Marijuana sniffing dogs are trained to look for the smell of Caryophyllene.(Source) Β-Caryophyllene is the first FDA approved cannabinoid.

Source:

http://www.leafscience.com/2014/07/08/b-caryophyllene-terpene-anxiety-depression/

http://www.sciencedirect.com/science/article/pii/S0031938414003400

http://en.wikipedia.org/wiki/Caryophyllene

http://www.sciencedirect.com/science/article/pii/S0091305714001956

How Cannabis Effects the Endocannabinoid System

Cannabis has a profound effect on our body due to it's influence on our endocannabinoid system. The origin of its name comes from the cannabis plant. It is a system of lipids and receptors that maintain health creating a homeostasis environment in the body. The endocannabinoid system is found throughout our body in the brain, organs, connective tissues, glands and immune cells. The prevalence of the endocannabinoid system in the body is the reason cannabis can treat many diverse diseases and symptoms.

Environmental factors can cause disruption in the bodies health. Stability is brought back with the endocannabinoid system. The goal for the lipids and receptors are to stabilize numerous body functions including appetite, pain, inflammation, mood, memory, muscle spasms, protect nerves, immunity, and bone density. Cannabis would be the closest cure-all for its ability to affect so many functions in the body.

The endocannabis system is made up of ligands like anandamide and 2-arachidonoylglycerol (2-AG). The cannabinoid CB1, CB2, TRPV1 and G protein-coupled receptors are part of the endocannabinoid system. Together these ligands and receptors control the stabilization of the body.

Cannabis can encourage more endocannabinoids and receptors to be made by the body. First-time users of cannabis may not feel an effect from cannabis. As the body increases cannabinoids it responds more effectively to a cannabis treatment. Smaller doses have larger effects for the receptors to respond to marijuana.(Source)

Source:

http://en.wikipedia.org/wiki/Endocannabinoid_system

http://norml.org/library/item/introduction-to-the-endocannabinoid-system

Beta Myrcene is the Most Common Terpene in Cannabis

Beta Myrcene is the most common terpene found in cannabis. It has a spicy herbal scent that is known to aid in treatment to pain, inflammation and muscle relaxation. This terepene is also found in bay leaves, eucalyptus, hops, lemongrass, mangos, parsley and thyme. The high amount of β-Myrcene in Indica strains are what give the “couch-lock” sedative effect.(Source)

Myrcene, or β-myrcene is a monoterpene which is a volatile compound that evaporates quickly with exposure to air. It is known as an essential oil for its fragrance and is used for menthol and citronella products. Cannabis strains that contain high amounts of Beta Myrcene are White Widow and Neville's Haze.(Source)

The benefits of Beta Myrcene are found in it's analgesic, anti-tumor, anti-inflammatory, sedative and ability to reduce muscle spasms. Lemon grass tea is known for it's pain relieving effects due to it's high content in β-myrcene. Studies with high content of Myrcene in mice have shown a sedative quality. The terpene has a unique ability to intesify the effects of the CB1 receptors in the body which helps in inflammation and pain relief.

Myrcene lowers the resisistance across the blood brain barrier. This effect makes other chemicals like THC to absorb and take effect more quickly. Indica strains in cannabis offer a .5% or greater potency in myrcene allowing for better delivery of THC and it's effects. Sativa strains typically contain less than .5% which allows the effects to be more subtle. It has been found that eating a mango a half hour before smoking cannabis increases the psycho active effects for it's high content of β-Myrcene.

Source:

http://pubchem.ncbi.nlm.nih.gov/compound/31253?from=summary

http://en.wikipedia.org/wiki/Myrcene

http://steephilllab.com/resources/cannabinoid-and-terpenoid-reference-guide/

http://www.ncbi.nlm.nih.gov/pubmed/24956819

http://www.marqaha.com/#!under-microscope/c1cbz

Cannabis Treatment for Rheumatoid Arthritis

Rheumatoid Arthritis (RA) is an autoimmune disease that affects the joints. The symptoms are pain, inflammation and stiffness. Doctors treat RA by reducing pain, inflammation and slowing down joint damage.(Source)

A study in 1998-2002 found that illicit cannabis in the U.K. greatly reduced rheumatoid arthritis pain. The survey found that 100% of the RA sufferers found cannabis reduced symptoms “much better” (72%) or “a little better” (28%).(Source) A study in 2006 with the Cannabis Medicine Savitex showed significant improvement in pain and reduced disease activity.(Source) A 2005 survey of medical cannabis patients in Australia showed that 25% used it to treat rheumatoid arthritis.(Source)

Cannabis helps treat rheumatoid arthritis because of it's ability to reduce joint pain, inflammation and increase immunity. The endocannabinoid system affects receptors in the nervous that target joint tissue and immune cells.(Source) Cannabinoids affect the activity of the COX-2 enzymes which contribute to inflammation from arthritis.(Source) Cannabinoids also have immunosupressive properties which curtail inflammatory molecules called cytokines.(Source)

Souce:

http://www.niams.nih.gov/Health_Info/Rheumatic_Disease/rheumatoid_arthritis_ff.asp

http://rheumatology.oxfordjournals.org/content/45/6/781.1.full

http://www.ncbi.nlm.nih.gov/pubmed/16282192

http://www.harmreductionjournal.com/content/2/1/18

http://www.arthritistoday.org/arthritis-treatment/natural-and-alternative-treatments/remedies-and-therapies/medical-marijuana.php

http://www.researchgate.net/publication/51088411_Evaluation_of_the_cyclooxygenase_inhibiting_effects_of_six_major_cannabinoids_isolated_from_Cannabis_sativa

http://www.cannabis-med.org/data/pdf/2001-03-04-5.pdf

Cannabis Begins it's Medicinal Benefits with Cannabigerolic acid (CBGa)

CBGa is Cannabis in the Raw

All cannabinoids start out as cannabigerolic acid (CBGa). Eating raw fresh cannabis that contains CBGa has medicinal benefits with different effects than other cannabinoids. As a result of it's non-psychoactive nature CBGa can be consumed in larger quantities than THC.

Fresh and raw cannabis typically breaks down CBGa into other cannabinoids quickly after harvest. Some industrial hemp strains have shown to have CBGa that doesn't convert to other cannabinoids. It has been speculated that these strains hold a recessive gene which doesn't allow this conversion. If a strain has a high CBGa content then smoking it will add heat and change it to CBG.(Source)

CBGa has been found to interact with a different cannabinoid receptor than THC. Ruth Ross from the University of Aberdeen found that CBGa was an antagonist for the cannabinoid receptor GPR55. She found that CBGa and CBDa were 2-4 times stronger in affecting GPR55 than CBD and CBG.(Source) GPR55 has shown to target inflammatory pain, neuropathic pain and aid in bone development.(Source)

Dr. William Courtney ,a leading physician advocating the use of raw cannabis, says:

“If you heat the plant, you get decarboxylated THCa – THC, and you will have psychoactive effects with only 10mg of THC. If it is not heated, you can take from 500 to 600 mg of THCa, use it as essential nutrient and enjoy the antioxidant and neuroprotective properties that these high doses offer you.”

In the raw form cannabis gives a powerful dietary component of essential fatty acids, essential aminoacids, fibers, enzymes, vitamins, minerals, flavonoids, carotenoids, terpenes and of course phytocannabinoid acids. (Source)

Source:

http://www.medicaljane.com/2013/08/03/cannabigerol-cbg-is-a-minor-cannabinoid-with-major-impact/

http://www.jbc.org/content/287/1/91.full.pdf

http://grantome.com/grant/NIH/R01-DA023204-08

http://www.alchimiaweb.com/blogen/dr-courtneys-raw-cannabis-juice/

CBD Helps with Intervertebral Disc Degeneration

  

Intervetebral Disc Degeneration

On December 17^th, 2014 a study was published on how cannabis can benefit Intervertebral Disc Degeneration. This study was a small sample done on mice. The results coincide with other findings that cannabis helps with inflammation in cartilage such as rheumatoid arthritis.(Source)

 Intervertebral discs are in between the vertebrae of the spine. The discs are a cartilage joint that allows movement in the spine. They serve a crucial purpose to absorb shock and act as a ligament to hold the vertebrae together.(Source)

  Disc degeneration is caused from inflammation, metabolism of cells and neo-innervation. Cannabidiol CBD has shown to have anti-inflammatory properties, reducing metabolism of bone cells and a nerve protect-ant. This new study is the first to explore the use of CBD in helping disc degeneration. The results concluded that the higher dosage of CBD showed improvement in the Invertebral Discs.(Source)

Source:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269422/

http://en.wikipedia.org/wiki/Intervertebral_disc

http://norml.org/library/item/rheumatoid-arthritis

CBD Tinctures

CBD Tinctures at OUTCO

OUTCO offers CBD Tinctures at the El Cajon Dispensary or Free Delivery for your convenience. Patients describe Cannabidiol (CBD) as treatment for pain, depression, anxiety, muscle spasms, and inflammation. Clinical research has shown CBD to be anti-bacterial, reduce cancer cells, a bone stimulant and a neuroprotectant. CBD is the cannabinoid in marijuana that has the most known benefits without a psychotic effect.

Typically patients use the tincture by putting 1-3 drops under their tongue. More drops can be used as needed. OUTCO has a proprietary method of extracting the CBD to a high concentrated form. Tinctures come in a choice of glycerin or alcohol. Glycerin patients describe as tasting better, while alcohol seems to provide more immediate relief.

The Benefits of Cannabichromene (CBC)

     

Cannabichromene CBC Creates Brain Stem Cells

  Cannabichromene (CBC) is a cannabinoid in marijuana that is in low concentration but high in healing properties. Research has shown that CBC helps in pain, depression, inflammation, bone growth, increase brain cells and reducing cancerous tumors. More research is needed but many scientists believe that CBC in conjunction with the other cannabinoids work together as a whole to provide the best medicinal effects.

   Cannabigerolic Acid (CBCA) is the initial cannabinoid form that the raw cannabis plant starts with. With age and oxidation this quickly breaks down with enzymes into CBDa, THCa and CBCa. The CBCa form when heated will lose a CO2 molecule allowing it to convert to Cannabichromene (CBC).

   CBC effects with the brain are exciting and promising for modern medicine to help with Alzheimer's and dementia. An Italian study found that CBC promotes brain cell growth with adult neural stem cells. Studies have shown that adults brain cell growth slows and the decline can lead to memory loss. Though the studies are with mice so far, the study done by GW Pharmaceuticals gives hope for a treatment for degenerative brain diseases.(Source) 
 

   CBC has also shown to reduce cancer cells and shrink tumors along with the cannabinoids CBD and CBG. They allow anandamide to inhibit cancer cell growth. Cannabidiol (CBD) shows the highest potency with CBC and CBG being next in potency. Allowing all cannabinoids to work synergistic-ally allows them to target different receptors to inhibit cancer growth. (Source)

Other great benefits include:

• Bacteria like Staph and E.Coli showed inhibited by CBC. (Source)
• CBC has been found in studies to be an anti-inflammatory in mice. (Source)
• CBC targeting the nervous system to control pain at a chronic level.(Source)
• Euphoric uplifting properties are given with CBC that works differently than THC. (Source)
• CBC acts as a bone-stimulant (Source)

Source:

http://www.medicaljane.com/2013/08/14/cannabichromene-cbc-is-the-most-disregarded-cannabinoid/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417459/
http://www.sciencedirect.com/science/article/pii/S0197018613002106
http://montanabiotech.com/2011/09/20/breast-cancer-antitumor-effects-inhibition-of-cancer-cell-proliferation-and-treatment-using-medical-cannabis-marijuana-derived-cannabinoids-tetrahydrocannabinol-cannabidiol-cannabigerol-cannabichromen/
http://www.ncbi.nlm.nih.gov/pubmed/20942863

http://www.delta9.ca/resources/Cannabinoids%20-%20General/Cannabinoids%20Primer%20New.pdf

The Benefits of Cannabigerol (CBG)

  Cannabigerol CBG is a cannabinoid in marijuana that has medicinal properties. Found in low concentrations in many strains of cannabis it is often overlooked. CBG works in conjunction with THC to tone down the paranoia feeling.(Source) Alone it aids in treatment to depression, tumors, inflammatory bowel disease, glaucoma, bacteria infections, high blood pressure, reduce blood clotting, anxiety and muscle tension.

   Research has proven many treatments from Cannabigerol. Here is a list of the numerous benefits of CBG:

Depression: GW Pharma has a patent for the use of Cannabigerol CBG to treat clinical depression.(Source)

Cancer \Tumors: New research this year has shown that CBG reduces cancer cells and tumors in the colon.(Source)

Inflammatory Bowel Disease: CBG reduced inflammation and over-production of nitric oxide which can lead to sustained IBD.(Source)

Glaucoma: CBG shows promising treatment for glaucoma by relieving ocular pressure. More importantly CBG showed 2-3 times the benefit of eye drainage than other medicines.(Source)

Bacterial Infections: Bacterial infections have been treated including MRSA.(Source)

Reduce Heart Rate and Blood Clotting: Has shown as a proven treatment for the way it reduces platelet aggregation.(Source)

Anxiety and Muscle Tension: CBG is able to treate with it's ability to inhibit GABA production.(Source)

Cannabis initially starts with creating cannabinoid cannabigerolic acid (CBGa). This is typically broken down with exposure to air and UV light into THCa, CBDa or CBCa. If it remains as CBGa, then it will convert to CBG when heated. Some industrial strains retain the CBGa with as much as a 94% concentration. It is thought this strain has a recessive gene that doesn't allow the conversion to the THCa, CBDa or CBCa. Currently some growers are using this knowledge to create strains rich in CBG like the Mickey Kush Strain.

Source:

http://www.medicaljane.com/2013/08/03/cannabigerol-cbg-is-a-minor-cannabinoid-with-major-impact/

http://www.ncbi.nlm.nih.gov/pubmed/25269802

http://www.sciencedirect.com/science/article/pii/S0006295213000543

http://www.google.com/patents/CA2655094C?cl=en

http://www.amazon.com/Cannabis-Therapeutics-HIV-AIDS-Journal/dp/0789016990/ref=sr_1_1?s=books&ie=UTF8&qid=1418758497&sr=1-1&keywords=9780789016997

http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.1989.tb06345.x/abstract

How Cannabis Treatment Reduces Multiple Sclerosis Symptoms

Cannabis and Multiple Sclerosis

Inflammation in multiple-sclerosis (MS) show positive results with cannabis. Symptoms benefiting from cannabis treatments are muscle spasms, pain, sleep, interocular pressure and incontinence.(Source) MS is a long-term disease that effects the brain, central nervous system and optic nerves. This disease makes the immune system attack a fatty material called myelin. This fatty tissue wraps around the nerve fibers to protect them. The scar tissue of myelin called sclerosis causing inflammation.(Source)

Cannabis has shown to prevent inflammation in the central nervous system. Dr. Ewa Kozela of Tel Aviv University, Israel says "Inflammation is part of the body's natural immune response, but in cases like MS, it gets out of hand". In the Journal of Neuroimmune Pharmacology he shows how cannabis can regulate inflammation.

In Dr. Kozela's study the cannabinoids tetrahydrocannabinol (THC) and cannabidiol (CBD) found in marijuana reduced inflammation associated in MS. The cannabinoids when administered reduced the inflammatory molecules, notably interleukin 17 (IL-17). The researchers say the inflammatory molecule "is strongly associated with MS and very harmful to nerve cells and their insulating covers,". They concluded:

"The presence of CBD or THC restrains the immune cells from triggering the production of inflammatory molecules, and limits the molecules' ability to reach and damage the brain and spinal cord." (Source)

Source:

http://www.webmd.com/multiple-sclerosis/guide/what-is-multiple-sclerosis

http://www.neurology.org/content/65/6/812.abstract

http://medicalmarijuana.procon.org/view.resource.php?resourceID=000884

http://www.medicalnewstoday.com/articles/267161.php

What is 2-AG and Does it Relate to Cannabis?

   2-Arachidonoylglycerol (2-AG) is the most abundant endocannaboinoid messenger molecule that effects the TRPV1, CB1 and CB2 receptor. 2-AG is 170 times the concentration of anandamide which also effects the same receptors. 2-AG is naturally created in humans and also found in human and cattle milk. (Source)

   So why does this matter? Because 2-AG and anandamide is created on-demand naturally by the body, and an imbalance to the body to produce too much or little is thought to lead to disorders. Drug therapies that target the CB1, CB2 receptors bring the body back to a balance where 2-AG is lacking.(Source) It is theorized that diseases such as bipolar(Source) and alzheimer's(Source) could occur from an imbalance of 2-AG being created in the body.

   The nerve cells affected by 2-AG control body temperature, appetite, memory, mood, inflammation, immunity and the sensation of heat and pain. Studies show that it may inhibit cancer cell formation. 2-AG is created from 20-carbon essential fatty acids (EFA). Cannabis is a good source of EFA's that mimics 2-AG functions.(Source)

   Cannabis drug therapies have been developed to treat symptoms of many problems by mimicking the 2-AG messenger molecule. Some examples of treatment are for memory, pain, nausea, wasting syndrome, cancer, spasticity from multiple sclerosis and tremors from Parkinson's disease.

   2-AG plays an important role in traumatic brain injuries. When a brain injury occurs 2-AG has been found to be elevated. A study with mice was done where they gave a drug to boost the levels of 2-AG after a brain injury. The results were a quicker recovery, reduced inflammation, swelling and brain cell death.(Source)

Source:

http://en.wikipedia.org/wiki/2-Arachidonoylglycerol

http://sensiseeds.com/en/blog/cannabinoid-science-101-what-is-2-ag/

https://www.caymanchem.com/app/template/Article.vm/article/2110

http://www.ncbi.nlm.nih.gov/pubmed/21175579

http://bipolarnews.org/?tag=cannabidiol

http://www.jneurosci.org/content/34/45/14919.short

http://www.ncbi.nlm.nih.gov/pubmed/11586361

Cannabis Strains that are High in CBD

Most cannabis strains on the market are bred for their cannabinoid potency in THC, which is the active part that give a psycho effect. There are 85 active cannabinoids that are known in cannabis and cannabidiol or CBD is growing in popularity for it's high effectiveness for medicinal use without the psycho-active properties.

Treatment with Cannabidiol CBD

Cannabidiol in marijuana is the second most prevalent cannabinoid behind THC. At first it was thought the only benefit of CBD was to counteract the stoned effect that THC gives. However, CBD has been shown in research to give anti-inflammatory, analgesic and lower anxiety without the psycho-active effects that THC gives. These benefits have shown promising results for treatment in crohn's disease, PTSD, multiple sclerosis and a form of epilepsy called Dravet's Syndrome. Strains high in THC are usually at levels of 20% above, where CBD over 4% are known to be in high concentration. The FDA is approving a study this year to look at the effectiveness of CBD in children to hopefully make this a more accessible treatment.(Source)

Many patients are vocal about the importance of THC with CBD for complete effectiveness as a treatment. The government has acquired a patent for the benefits in THC, and research has showed it to help with appetite loss, nausea, multiple sclerosis and pain. Allowing to manage the percentage amount of THC and CBD gives the most effectiveness as well as also having control of how it is consumed. (Source)

Strains that are High in CBD

   The strains listed give different concentrations of CBD to THC ratios and also differentiate with their terpene properties to give different medicinal effects.

AC/DC - Sativa dominant 1:20 ratio of THC:CBD, a phenotype of Cannatonic

Cannatonic – Hybrid with 1:1 ratio. Origins are MK Ultra X and G-13 Haze.

Canna Sue – 13.8%CBD to 10.4%THC from Southern Humbolt Seed Company cross of Canna Tonic and Sour Tsunami

Charlotte's Web – Sativa dominant created by the Stanley brothers

Harlequin – Sativa Hybrid, registered 11.6%CBD to 8.4%THC (Source)

Harle Sue – Sativa Hybrid, registered 9.4%CBD to 6.7%THC, cross of Harlequin and Sour Tsunami

Jamaican Lion – Sativa with 1:1 ratio or better, cross between Mountain Lion and Yarders.(Source)

Omrita Rx – Indica dominant, 9.5% CBD to 11% THC, lots of leaves to juice, High in Beta Caryophylline.

Oracle* found to be identicle to AC/DC

Sour Tsunami – Sativa hybrid with 7.24%CBD to 4.32%THC ratio from Humboldt Seed Company

Women's Collective Stinky Purple

Swiss Gold – Sativa hybrid 7.2%CBD and 3.6%THC

Valentine X – Hybrid known to be highest CBD ratio 25:1, a phenotype of AC/DC

(Source)(Source)

Source:

http://www.projectcbd.org/medicine/strain-library/

http://www.leafly.com/news/lifestyle/whats-the-deal-with-these-high-cbd-strains

http://www.mpp.org/assets/documents/low-or-no-thc-high-cbd.html

http://synergycbd.com/cdb-rich-strains/

http://www.hydrocanna.com/showthread.php?t=9683

Cannabis and Pain Management

One hundred million Americans suffer from chronic pain.(Source) Three to four percent of the global population suffer from neuropathic pain. (Source) Pain contributes to feeling depressed, concentration, energy level, ability to sleep well and enjoyment of life. (Source) Cannabis has been found to be an effective treatment in neuropathic pain, fibromyalgia, rheumatoid arthritis and pain from cancer. Cannabis has been found to be safer with less side effects than opiate medication.(Source)

Cannabis has been found to effectively relieve neuropathic pain. Both Cannabis and Opiates target the G-protein-coupled receptors (GPCRs). These receptors effect the Central Nervous System CNS using the CB1 and CB2 Receptors, which effect pain-sensation, and mood notably. (Source)

Fibromyalgia is a muscleskeletal pain resulting in fatigue and pain in the neck, spine, shoulder and hips. Three to six million Americans suffer from fibromyalgia. In 2006, a study in Germany giving THC to patients showed a significant relief in symptoms. A study in 2008 with 40 patients gave a synthetic cannabinoid and showed significant improvements in pain. And in 2011 a study in Barcelona and the patients reported significant relief in pain, stiffness, relaxation, somnolence and feeling of well-being.(Source)

Cannabis has been found in studies in Australia and Britain showed that 20% of patients suffering from Rheumatoid Arthrites (RA) used medical marijuana to help treat their symptoms.(Source) Cannabis is an anti-inflammatory and helps to turn off pain-sensations in the nerves from the interactions it has with CB1 and CB2 Receptors. Results in a study in Britain showed that their were significant improvements in pain, sleep and inflammation.(Source) Cannabidiol CBD found in marijuana has shown to stop the progression of Rheumatoid Arthritis and protected joints. (Source)

A research study showed that advanced cancer patients were able to reduce their pain by 30% using a THC:CBD extract. In the study, with 177 patients, opiate medications did not provide the necessary relief. The placebo and THC alone had similar results to the opiate medication where the THC:CBD cannabis extract showed a noticeable relief in pain.(Source)

Cannabis has been found to have less side effects than opiate medication. A study has found that states that have legal medical marijuana has less mortality rates due to overdose in pain medication. (Source) Cannabis has been found to help patients addicted to opiate drugs withdraw from addiction by replacing with medical marijuana, and perceived to help pain more.(Source) Pain sufferers that have achieved a tolerance with opiate medication can feel a better relief by replacing treatment with cannabis.(Source) Cannabis can be used with opioid therapies to help lower the dose of opiates, thereby reducing their side effects. (Source)

Source:

http://books.nap.edu/openbook.php?record_id=13172&page=1

http://www.prweb.com/pdfdownload/8052240.pdf

2006 Voices of Chronic Pain Survey. (American Pain Foundation)

http://en.wikipedia.org/wiki/Medical_cannabis

http://ajh.sagepub.com/content/28/5/297

http://www.ncbi.nlm.nih.gov/pubmed/?term=25154332

http://www.ncbi.nlm.nih.gov/pubmed/?term=19896326

http://www.ncbi.nlm.nih.gov/pubmed/22880540

http://www.ncbi.nlm.nih.gov/pubmed/?term=22048225

http://www.humboldt.edu/hjsr/docs/fwhjsrparagraph/Issue%2035%20Second%20Article%20Peters.pdf

http://www.ncbi.nlm.nih.gov/pubmed/?term=19857996

http://rheumatology.oxfordjournals.org/content/45/1/50.abstract

http://norml.org/library/item/rheumatoid-arthritis#3

Cannabis as a Treatment for Diabetes

Diabetics can have many reasons to use cannabis as a way to reduce diabetes related problems. Here is a bullet point list of the problems that diabetics face and how marijuana can help from letfreedomgrow.com:

• Increases Blood Flow to Extremities - Cannabis inhibits the overproduction of prostoglandins, a hormone that dilates and constricts blood flow. Cannabis is a vasodialator that helps blood flow. Marijuana is a powerful antioxidant which helps decrease free radical damage and helps inflammation. For these reasons it allows cannabis to be a great treatment for arterial inflammation, common in diabetics. Topical creams on the extremities can help with instant relief.


• Over Time Reduces Blood Pressure – This is in conjunction with the previous from being a vasodialator. If cooking butter and oil is replaced with Cannabis oil and butter, the saturated fats from the old method of cooking will be eliminated and replaced with essential fatty acids.


• Muscle Cramps and Gastro Intestinal Upset – Many diabetics have these symptoms which are helped by cannabis for its ability to be neuroprotective. Cannabis helps the nerve covering from inflammation. Cannibidiol form of cannabis is best known for counteracting spasms.


• Blood Sugar Levels - One problem with research on cannabis is the criminalization of the drug that inhibits proper research to find if a treatment is conclusive or not. Sugar level may be regulated through cannabis from a reduction in Catecholamines. This is a hormone from the adrenal gland that produces epinephrine ( adrenalin ), norepinephrine and dopamine from emotional stress. Cannabis cookies can be used if in moderation to help control blood sugar levels.


• Restless Leg Syndrome RLS – Many diabetics suffer from restless leg syndrome and the cramping of the muscles that may be a result from the nervous system can be reduced by Cannabis in the way it controls the prostoglandins to relax muscles and it's neuroprotective properties. Using a nightime vapor or smoking before sleeping can reduce the symptoms, with the strains of Oregon 90, Lemon Haze, and White Berry being the best.

OUTCO is San Diego's only legally licensed medical marijuana dispensary offering FREE Delivery and Accepting Debit Cards.

Source:
http://www.letfreedomgrow.com/cmu/diabetes_5.htm