Thursday, November 20, 2014

Cannabis and the Type 1 Vanilloid Receptor

TRPV1 also known as Type 1 Vanilloid Receptor, Capsaicin Receptor and transient receptor potential cation channel subfamily V member1 is a protein that the TRPV1 gene encodes. This receptor regulates body temperature and the sensation of heat and pain. Found in the nervous system it is a communicator of pain to the brain, and desensitizing gives a analgesic pain free feeling.
Cannabinoids found in marijuana have been found to be an antagonist to the TRPV1 receptor, which can help with neurpathic pain, multiple sclerosis, chemotherapy, amputation as well as osteoarthritis, anxiety and long term depression.(Source) Cannabidiol CBD has shown to have an activation of the TRPV1 receptors. (Source) Endocannabinoid anandamide that is affected by the use of cannabis has been shown to act on the TRPV1 receptors as well. (Source) Dopamine which is increased with cannabis use also effects the TRPV1 receptor.(Source)


Along with treatment in symptoms, cannabis can reduce cancer to it's role in the TRPV1 receptor. Neuroblastoma is a cancer started in the nervous system in the human fetus or embryo that resides in the nervous system. This form of cancer is usually seen in young children before the age of 10. Research has shown that cannabis can delay or stop the cancer cell growth of neuroblastoma by activating the TRPV1 receptors. (Source)


Source:
http://www.ncbi.nlm.nih.gov/pubmed/17442052

2 comments:

  1. Sandra Wilkinson and her 9-year old daughter Mia at Canadian Cannabis Clinics in St. Catharines on Monday, September 14, 2015. Mrs. Wilkinson brought Mia to this Ontario clinic because she could not get her prescription for Cannabis Oil renewed at their home in Alberta. Mia has been taking Cannabis oil for two years. She went from having 100 seizures a day to being seizure-free for about a year and a half. READ MORE AT http://www.edmontonjournal.com/Sandra+Wilkinson+year+daughter+Canadian+Cannabis+Clinics+Catharines+Monday+September+2015+Wilkinson+brought+this+Ontario+clinic+because+could+prescription+medical+marijuana+renewed+their+home+Alberta+been+taking+medical+marijuana+years/11364755/story.html

    I got a recommendation online about someone with the E-mail: (info.cannabismedsdelivery@gmail.com) and Skype: (medical.cannabis) who supplies High CBD Cannabis Oil and I Ordered from him and believe me the Cannabis Oil I got has helped me with several medical issues like Treating Cancer, Severe Pain, Depression, Seizure disorders and Crohn's disease.
    My Fellow Brothers & Sisters, We don't need to Runaway from the Cure even though the Government have made it illegal.

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